Active Follow-up in Patients with Localized Prostate Cancer: Evaluation of Long-term Results

Authors

  • S.O. Vozianov State Institution «Institute of Urology of National Academy of Medical Sciences», Kyiv, Ukraine
  • V.M. Grygorenko State Institution «Institute of Urology of National Academy of Medical Sciences», Kyiv, Ukraine
  • R.O. Danylets State Institution «Institute of Urology of National Academy of Medical Sciences», Kyiv, Ukraine
  • A.V. Bardin State Institution «Institute of Urology of National Academy of Medical Sciences», Kyiv, Ukraine
  • L.V. Pereta State Institution «Institute of Urology of National Academy of Medical Sciences», Kyiv, Ukraine

DOI:

https://doi.org/10.22141/2307-1257.0.2.04.2013.85343

Keywords:

prostate cancer, active follow-up, Gleason grading, prostate specific antigen

Abstract

Among the clinical recommendations one of the standard approaches in the treatment of prostate cancer is active follow-up. For 13 years, under the supervision there were 85.7 % of patients. Overall 3-, 5- and 7-year survival rate was 93.2 ± 4.6 %, 70.8 ± 9.1 % and 50.9 ± 10.2 %, respectively. 14.3% of patients died due to comorbidities. The average time of survival was 136 months.
These data substantiate the feasibility of active follow-up from medical, social and economic point of view. Optimal results can be achieved with the right selection, the criteria of which are: the level of prostate-specific antigen ≤ 10 ng/ml, Gleason grading score ≤ 6, age, multiple organ pathology.

Downloads

Download data is not yet available.

References

Berger I.M. Prostate cancer in senior adults: over- or undertreated? / Berger I., Böhmer F., Ponholzer A., Böhmer F. [et al.] // S. Med. Wochenschr. — 2009. — Vol. 159, № 21–22. — P. 521-528.

Gittes R.F. Carcinoma of the prostate / R.F. Gittes // Engl. J. Med. — 1991. — Vol. 324(4). — P. 236-245.

Koppie T.M. Patterns of treatment of patientswithprostate cancer initially managed with surveillance: results from The CaPSUREdatabase. Cancer of the Prostate trategic Urological Research Endeavor / T.M. Koppie, G.D. Grossfeld, D. Miller [et al.] // J. Urol. — 2000. — Vol. 164(l). — P. 81-88.

Johansson J.E. Natural History of Early, Localized Prostate Cancer / J.E. Johansson, O. Andren, S.O. Andersson et al. // JAMA. — 2004. — 291. — 2713-2719.

Klotz L. Clinical Results of Long-Term Follow-Up of a Large, Active Surveillance Cohort With Localized Prostate Cancer / L. Klotz, L. Zhang, A. Lam, R. Nam, A. Mamedov, A. Loblaw // J. Clin. Oncol. — 2010. — Vol. 1, № 28(1). — P. 126-131.

Published

2022-02-15

How to Cite

Vozianov, S., Grygorenko, V., Danylets, R., Bardin, A., & Pereta, L. (2022). Active Follow-up in Patients with Localized Prostate Cancer: Evaluation of Long-term Results. KIDNEYS, (2.04), 7–10. https://doi.org/10.22141/2307-1257.0.2.04.2013.85343

Issue

Section

Guest Articles